Protection against ExperimentalStaphylococcus aureusArthritis by Vaccination with Clumping Factor A, a Novel Virulence Determinant
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چکیده
منابع مشابه
Protection against experimental Staphylococcus aureus arthritis by vaccination with clumping factor A, a novel virulence determinant.
The importance of the fibrinogen-binding adhesin clumping factor A (ClfA) in the pathogenesis of Staphylococcus aureus septic arthritis was examined in an animal model. The protective effect of active and passive immunization with ClfA also was investigated in S. aureus infection models. The severity of arthritis was markedly reduced in mice challenged intravenously with a clfA mutant, compared...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2001
ISSN: 0022-1899,1537-6613
DOI: 10.1086/324430